Platelet Aggregation and Adenosine Levels Among Patients Taking Ticagrelor or Prasugrel

• Status: Completed
• Trial end date: 2021-12-20
• Target enrollment: 0
• Participant gender: All

Summary

Prospective, single-center, double blind, double dummy, randomized trial. Platelet function tests and adenosine levels were assessed at baseline and 15 days after taking Ticagrelor with Prasugrel placebo or Prasugrel with Ticagrelor placebo in stable patients with coronary artery disease

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Sao Paulo
• Treatments: Prasugrel Hydrochloride; Ticagrelor

Criteria

Inclusion Criteria:

• between 18 and 75 years old

• were on aspirin

• without P2Y12 inhibitor at baseline

• > 1 year after documented acute coronary syndrome

Exclusion Criteria:

• use of oral anticoagulation or P2Y12 at baseline

• Weight < 60kg

• History of tia or stroke

• Any coagulation disorders

• Refuse to sign the written consent