Plasma and Abscess Fluid Pharmacokinetics of Cefpirome and Moxifloxacin After Single and Multiple Dose Administration
Status:
Completed
Trial end date:
2009-12-01
Target enrollment:
Participant gender:
Summary
Penetration of cefpirome and moxifloaxacin into abscess fluid of humans will be tested.
Patients with an abscess scheduled for drainage will receive study drugs (single or multiple
dose), pus samples and plasma samples will be collected and analyzed by High pressure liquid
chromatography (HPLC). Pharmacokinetics of the study drugs in pus and plasma will be
determined using a pharmacokinetic model.
Phase:
Phase 4
Details
Lead Sponsor:
Medical University of Vienna
Treatments:
Cefpirome Cephalosporins Fluoroquinolones Moxifloxacin Norgestimate, ethinyl estradiol drug combination