Overview

Plasma Triglyceride Extraction by The Muscle

Status:
Completed
Trial end date:
2016-08-31
Target enrollment:
Participant gender:
Summary
Increased accumulation of fat into the muscles is associated with what is called insulin-resistant state, which is a pre-diabetic state. The purpose of this research is to find out how fat circulating in the blood following fat consumption is taken up by the muscles in healthy people as well as people that are insulin-resistant. The investigators are specifically interested in how a hormone called insulin is involved in this process. Findings from this research will contribute to our understanding of why insulin-resistant people have increased accumulation of fat in their muscles, and ultimately help to design appropriate interventions to prevent type 2 Diabetes.
Phase:
Phase 1
Details
Lead Sponsor:
Mayo Clinic
Collaborator:
American Diabetes Association
Treatments:
Insulin
Insulin, Globin Zinc
omega-N-Methylarginine