Plasma Glucose Levels With Dexamethasone as Adjuvant to Interscalene Block

• Status: Withdrawn
• Trial end date: 2013-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine the Finger Blood Glucose (sugar) when dexamethasone is added to a local anesthetic for a shoulder nerve block procedure. The investigators hypothesize that there is no increase in plasma glucose when 8 mg of dexamethasone is used as an adjuvant with local anesthetic to interscalene regional anesthesia. By performing finger stick blood glucose measures pre/peri and post operatively the investigators will be able to determine if any such increase exists.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Lifespan
• Collaborator: United States Naval Medical Center, Portsmouth
• Treatments: Anesthetics; BB 1101; Bupivacaine; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate

Criteria

Inclusion Criteria:

• ASA 1 or ASA 2 male or female non pregnant patients undergoing elective shoulder arthroscopy for surgical repair.

Exclusion Criteria:

• severe lung disease

• contralateral diaphragmatic paralysis

• coagulopathy

• pregnancy

• pre-existing neuropathy involving the surgical limb

• systemic use of corticosteroids for 2 weeks or longer within 6 months of surgery

• chronic opioid use (30 mg oral oxycodone equivalent per day)

• diabetes I or II

• diagnosis of "pre-diabetes"

• currently prescribed any of the oral glucose medications :sulfonylureas, meglitinides, biguanides, thiazolidinediones, alpha-glucosidase inhibitors, or DPP-4 inhibitors.