Plasma Concentrations of Bupivacaine After Peri-articular Injection in Total Knee Arthroplasty

• Status: Completed
• Trial end date: 2014-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Patients with knee arthroplasty usually performed under spinal anesthesia with a single-shot femoral nerve block and periarticular block, so we would like to know the plasma concentration of bupivacaine in these patients.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mahidol University
• Treatments: Bupivacaine

Criteria

Inclusion Criteria:

• age of 30-70 yr

• ASA I-II

• patient undergo total knee arthroplasty under spinal block and single shot femoral nerve block and periarticular block

Exclusion Criteria:

• patient's refusal

• allergic to bupivacaine

• body weight less than 50 kg

• liver disease

• heart disease

• coagulopathy

• Hct<35%

• infection at both groin