Placebo Controlled Trial of Sodium Selenite and Procalcitonin Guided Antimicrobial Therapy in Severe Sepsis
Status:
Completed
Trial end date:
2013-06-01
Target enrollment:
Participant gender:
Summary
Severe sepsis and septic shock are diseases of infectious origin with a high risk of death.
The purpose of this study is to determine whether the intravenous application of selenium
(given as sodium-selenite) can reduce mortality in patients with severe sepsis or septic
shock. Additionally, it is investigated, whether the measurement of procalcitonin - a marker
of infection - can be used to guide anti-infectious measures in this disease.