Overview

Place of Antibiotics in the Postoperative Acute Lithiasic Cholecystitis

Status:
Completed
Trial end date:
2012-11-01
Target enrollment:
Participant gender:
Summary
Assess whether postoperative antibiotics after cholecystectomy for acute lithiasic cholecystitis little or moderately severe, is effective and therefore justified. The main objective is to compare the occurrence of postoperative infectious complications including surgical site infections (SSI) and remote infections after early cholecystectomy (performed within 5 days after onset of symptoms) for acute lithiasic cholecystitis (ALC) little or moderately serious (without organ dysfunction) with and without postoperative antibiotics. The secondary objectives are: - Rates of infectious complications according to duration of preoperative antibiotic - Influence of surgical drainage after surgery for occurrence of postoperative infectious complications - Analysis of the nature of infectious complications (surgical site infections, remote surgical site infections) - Comparison of germs found in the bile during the postoperative infectious complications - Duration of hospitalization - Readmission rate for surgical site infections - Rate of reoperation for surgical site infection - Overall mortality rate at 30 days - Mortality rates specific to 30 days
Phase:
Phase 3
Details
Lead Sponsor:
Centre Hospitalier Universitaire, Amiens
Treatments:
Amoxicillin
Amoxicillin-Potassium Clavulanate Combination
Anti-Bacterial Agents
Antibiotics, Antitubercular
Clavulanic Acid
Clavulanic Acids