Premature rupture of membranes (PROM) is a common occurrence of pregnancies at term. A delay
from PROM to labor is associated with an increased risk of intrauterine infection and
associated maternal and fetal morbidity; therefore, induction of labor (IOL) is recommended.
The ideal agent for IOL is not known, particularly among specific subpopulations. The primary
aim of this study is to determine if oxytocin (Pitocin) or oral misoprostol results in a
shorter interval to delivery after the start of induction among nulliparous women with
unfavorable cervical exams with term PROM.