Pioglitazone vs. Insulin Glargine in the Treatment of Secondary Drug Failure in Type 2 Diabetes

• Status: Completed
• Trial end date: 2006-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Pioglitazone and insulin glargine are equally effective in achieving glycemic control in secondary drug failure of type 2 diabetes but the mechanisms of actions are different.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Skane University Hospital
• Collaborators: Medical Research Council; Skane County Council Research & Development Foundation
• Treatments: Insulin; Insulin Glargine; Insulin, Globin Zinc; Pioglitazone

Criteria

Inclusion Criteria:

• type 2 diabetes

• inadequately controlled on 50% of maximal-dose of an insulin secretagogue and metformin

Exclusion Criteria:

• heart failure (NYHA II-IV)