Pioglitazone on Cardiac Function and Large Arteries (PICCOLA Study)

• Status: Completed
• Trial end date: 2010-04-01
• Target enrollment: 0
• Participant gender: All

Summary

This study aims to use a novel, sensitive, non-invasive scanning technique to investigate the effects of insulin-sensitizing agent pioglitazone, on heart and artery function.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Imperial College London
• Treatments: Pioglitazone

Criteria

Inclusion Criteria:

• Male or female of any age with Type 2 Diabetes

Exclusion Criteria:

• Subjects will be excluded if they have any of the following:

• Known coronary heart disease,

• Patients receiving Insulin,

• Uncontrolled hypertension (i.e. >160mmHg systolic or >95mmHg diastolic),

• Systolic dysfunction (ejection fraction <50%),

• Heart Valve Disease,

• Proliferative or pre-proliferative retinopathy,

• Severe hepatic or renal impairment.

• Possible pregnancy

• Malignancy