In patients with impaired glucose tolerance (IGT), the researchers want to study the relative
effects of pioglitazone, simvastatin, or the combination of both on:
- intima media thickness (IMT) as an easily assessed marker of atherosclerosis
- heart rate variability (HRV) as a marker of autonomic neuropathy
- flow-mediated vasodilatation (FMD) of the brachial artery as a marker of endothelial
function
- vascular and metabolic lab parameters
Phase:
Phase 4
Details
Lead Sponsor:
University of Leipzig
Collaborator:
Institut für Gesundheits- und Praxismanagement GmbH