Overview

Pilot Study of the Safety and Efficacy of Anakinra in Pulmonary Arterial Hypertension

Status:
Completed
Trial end date:
2018-06-07
Target enrollment:
Participant gender:
Summary
Pulmonary arterial hypertension (PAH) can result in right ventricular failure and death. Anakinra has been used in patients with left sided heart failure, and the present study looks to determine if anakinra is safe and effective in patients with PAH. To accomplish this goal, we plan to evaluate for exercise improvement (as assessed by cardiopulmonary exercise testing) in 10 patients with PAH on anakinra.
Phase:
Phase 1
Details
Lead Sponsor:
Virginia Commonwealth University
Treatments:
Interleukin 1 Receptor Antagonist Protein