Pilot Study of mTOR Inhibitor Therapy in Peutz-Jeghers Syndrome
Status:
Terminated
Trial end date:
2011-03-01
Target enrollment:
Participant gender:
Summary
Pilot study, Open-label, Phase II study of Everolimus.
Objective:
To determine if Everolimus can diminish large gastrointestinal polyps in patients with
Peutz-Jeghers Syndrome.
Methodology:
Polyp size and number will be compared to baseline by FDG-PET and CT and 12 months after
treatment with Everolimus. Since this is a pilot study, the polyps prior to treatment will
serve as the controls.