Pilot Study of Sleep Therapy and Biomarkers in Children With Autism Spectrum Disorders
Status:
Terminated
Trial end date:
2021-01-29
Target enrollment:
Participant gender:
Summary
The purpose of this study is to test the combined effect of melatonin and donepezil on
improving sleep and behavior in children with Autism Spectrum Disorders. Melatonin is a
natural neurohormone that helps regulate sleep and wake cycles. Donepezil is used to improve
mental function for people with Alzheimer's disease. Children with Autism Spectrum Disorders
are more likely to have problems sleeping than other children. This difficulty has been
linked to daytime behavioral problems and family stress.