Pilot Study of PUFA-optimized RUTF for Severe Acute Malnutrition

• Status: Completed
• Trial end date: 2014-07-01
• Target enrollment: 0
• Participant gender: All

Summary

To test whether a ready-to-use therapeutic food (RUTF) enriched with polyunsaturated fatty acids (RUTF-P) is as effective for the treatment of severe acute malnutrition (SAM) as standard RUTF.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Washington University School of Medicine
• Collaborator: University of Malawi
• Treatments: Amoxicillin

Criteria

Inclusion Criteria:

• kwashiorkor and/or marasmus

• 6-59 months of age

• lives in local area near enrollment site

Exclusion Criteria:

• recent (<4 months) therapeutic feeding for moderate or severe acute malnutrition

• chronic medical condition (eg, Down syndrome, other congenital syndrome, chronic heart disease) that may make feeding and growth difficult (not to include HIV or TB)

• caretaker refusal of 2 blood draws

• ineligibility for outpatient therapy (ie, severe illness or anorexia requiring inpatient therapy)

• caretaker expresses plans to move away from local area of clinic, making followup difficult