Overview

Pilot Study of Organic Nitrates on Endothelial Function in CAD Patients

Status:
Unknown status
Trial end date:
2010-01-01
Target enrollment:
0
Participant gender:
All
Summary
Organic nitrates increase levels of circulating endothelial progenitor cells (Thum et al., Arterioscler Thromb Vasc Biol. 2007 Apr;27(4):748-54). Here, we want to test the effects of two different organic nitrates (PETN, ISDN) on number and function of endothelial progenitor cells and endothelial function.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Julius-Maximilians University
Criteria
Inclusion Criteria:

- Coronary artery disease, 2- or 3-vessel disease

Exclusion Criteria:

- Acute myocardial infarction, acute heart failure, cancer, acute infections