Pilot Study of Etoposide-based Therapy and Hematopoietic Cell Transplantation for Hemophagocytic Lymphohistiocytosis
Status:
Terminated
Trial end date:
2016-05-01
Target enrollment:
Participant gender:
Summary
The investigators would like to propose a pilot study evaluating the efficacy of etoposide
combined with immunosuppressive agents for adult secondary hemophagocytic lymphohistiocytosis
(HLH), in order to prove out whether the modification of previous HLH-94 or HLH-2004 protocol
for childhood patients can improve the outcome and decrease the toxicities. The results of
this pilot study will be a base of a more-improved phase-2 protocol.