Pilot Study of Enalapril and Renal Function in Patients With IgA Nephropathy
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
OBJECTIVES: I. Determine the most sensitive outcome measures (functional or morphological) of
a progressive renal injury in patients with IgA nephropathy.
II. Determine which of these patients are destined to progress to further injury in order to
target them for therapy.
III. Elucidate the determinants of progression in those patients who exhibit evidence of
either increasing impairment of ultrafiltration capacity or ongoing destruction of nephrons.