Overview

Pilot Study Sorafenib as Bridge to Orthotopic Liver Transplantation (OLT)

Status:
Terminated
Trial end date:
2012-01-01
Target enrollment:
Participant gender:
Summary
Patients with either histological confirmation or clinical diagnosis who are candidate for orthotopic liver transplant(OLT) will receive Sorafenib 400mg 2 x day (BID) as a neoadjuvant (bridging) treatment until transplant. If patient progresses or falls outside of the Milan criteria on sorafenib patient can be treated per physician's discretion using local therapy. Patient will be followed until 30 days after the orthotopic liver transplant (OLT).
Phase:
Early Phase 1
Details
Lead Sponsor:
Case Comprehensive Cancer Center
Collaborators:
Bayer
Onyx Therapeutics, Inc.
Treatments:
Sorafenib