Pilot Study On The Role Of Nitric Oxide In Alpha 1-Adrenergic Vasoreactivity

• Status: Completed
• Trial end date: 2006-06-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a research project to test two study techniques among healthy adults. The procedures look at how blood flow is controlled by substances in blood vessels.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Crystal A. Gadegbeku
• Collaborators: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National Institutes of Health (NIH); University of Michigan
• Treatments: Adrenergic Agents; Nitric Oxide; Oxymetazoline; Phenylephrine

Criteria

Inclusion Criteria:

Healthy men and women:

• Age 18 to 55 years

• Who have Blood Pressure less than or equal to 120/80.

Exclusion Criteria:

Individuals with:

• Diabetes, lung disease

• Stomach disease, liver disease

• Blood vessel disease

• Kidney disease

• High blood pressure

• Heart disease

• Hereditary blood disorders

• Hematocrit (amount of red blood cells) less than 30%,

• Who smoke

• Women who are pregnant or lactating