Pilot 3D Contrast-Enhanced Ultrasound Imaging to Predict Treatment Response in Liver Metastases

• Status: Suspended
• Trial end date: 2021-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Patients are invited to participate in a research study of liver perfusion (how blood flows to the liver over time). Researchers hope to learn whether perfusion characteristics of liver metastases may be predictive of response to treatment and whether liver perfusion characteristics can be used to follow response to treatment. Patients were selected as a possible participant in this study because they are identified as having liver metastases

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Stanford University
• Collaborators: National Cancer Institute (NCI); Philips Healthcare

Criteria

Inclusion Criteria

• Provides written Informed Consent and is willing to comply with protocol requirements.

• Has at least 1 focal lesion in liver or kidney

• Patient may be (i) in the process of receiving treatment (1 scan session), (ii) never treated (3 scan sessions) or (iii) changing treatment regimen/ type and/or receiving a new form of treatment and/or has been on a treatment break ('holiday')(3 scan session)

• Is at least18 years of age.

Exclusion Criteria

• Is determined by the Investigator that the subject is clinically unsuitable for the study.

• Known right to left cardiac shunt, bidirectional or transient.

• Hypersensitivity to perflutren.

• Hypersenstivity to the contrast agent Definity.

• Pregnant and lactating women