Physiologic Response to Glucagon at Varying Insulin Levels
Status:
Completed
Trial end date:
2013-03-01
Target enrollment:
Participant gender:
Summary
The purpose of this research study is to test how different levels of insulin block the
effect of glucagon. Insulin is a hormone that lowers blood glucose. Glucagon raises blood
glucose. Both are natural hormones made by people without diabetes. Sensor-based blood
glucose control studies have been done by our research group using glucagon in small doses to
prevent hypoglycemia (low blood sugar). However, sometimes glucagon does not work to raise
blood sugar. The investigators believe this is because of too much insulin in the body. This
study will help determine how different levels of insulin in the body affect the ability of
glucagon to raise blood sugar.
Phase:
N/A
Details
Lead Sponsor:
Legacy Health System
Collaborators:
Juvenile Diabetes Research Foundation Oregon Health and Science University