Physiologic Monitoring of Antidepressant Treatment Response
Status:
Completed
Trial end date:
2002-09-01
Target enrollment:
Participant gender:
Summary
Study Objectives:
- to identify neurophysiologic effects of venlafaxine treatment in normal controls using
quantitative EEG (QEEG) cordance
- to examine the effects of venlafaxine on different rating scales measuring mood and
anxiety (e.g., Ham-D, BDI, SCL-90, POMS-BI, Visual Analog Mood Scale, SSRS, SASS,
Q-LES-Q and SF-36) as well as on measures of cognitive and psychosocial function (i.e.,
Stroop, PASAT, RAVLT, Trailmaking A and B, Digit-Symbol, Grooved Pegboard,
Multidimensional Health Locus of Control, Temperament and Character Inventory,
Interpersonal Support Evaluation List, Godin Leisure-Time Questionnaire, and Pittsburgh
Sleep Quality Index) in normal control subjects, and the association of changes in
cordance with changes in thinking and memory.
- to identify physiologic effects of venlafaxine treatment in normal controls using heart
rate and immune function measures