Photodynamic Therapy System for Patients With Refractory/Unresponsive Solid Tumors
Status:
Completed
Trial end date:
2002-12-01
Target enrollment:
Participant gender:
Summary
This multi-center photodynamic therapy study plans to treat patients with large tumors in any
superficial location, sarcoma, tumors of oral/oro-pharyngeal cavity, tumors with extensive
pelvic involvement, or liver metastasis. The treatment is limited to patients that have
failed to respond to currently approved methods of treatment. The study involves a single,
intravenous administration of an investigational drug, LS11 (previously studied in
approximately 80 cancer patients) and the placement of a novel, flexible light delivery
catheter inside the tumor by a minor surgical procedure. The activation of LS11 by the light
delivery catheter over a period of 1-24 hrs may result in destruction of tumor tissue.