Photo-induction as a Means to Improve Cisplatin Delivery to Pleural Malignancies
Status:
Terminated
Trial end date:
2018-08-28
Target enrollment:
Participant gender:
Summary
This clinical study aims to explore intrapleural low-dose Visudyne®-mediated photodynamic
therapy (photo-induction) as a pathway to promote the uptake of systemically administered
Lipoplatin™ in pleural malignancies of patients undergoing video-assisted talcage for their
malignant pleural effusions. Photo-induction is expected to overcome the chemo-resistance of
pleural malignancies for cisplatin-based chemotherapeutics and thereby improve local tumor
control.