Phenotypical Approach of the Drug Metabolizing Hormones Activity Before and After Roux-en Y-Gastric Bypass
Status:
Completed
Trial end date:
2014-02-01
Target enrollment:
Participant gender:
Summary
The activity of drug-metabolizing enzymes and transporters evolutes after Roux-en-Y gastric
Bypass.
Primary aim : To study the intra individual evolution of phenotypical markers of different
drug metabolizing enzymes and one transporter (CYP1A2, CYP2D6, CYP2C9, CYP2C19, CYP3A4 and
P-gp), using a cocktail phenotypic approach, after Roux-en-Y gastric Bypass.