Overview

Phase Ib/II Trials of RAD001 in Triple Negative Metastatic Breast Cancer

Status:
Terminated
Trial end date:
2017-07-30
Target enrollment:
Participant gender:
Summary
This study consists of two parts. In a phase Ib part, investigators will explore the recommended dose of gemcitabine, cisplatin, and RAD001 combination in patients with metastatic TNBC. After completing the phase Ib part, investigators will review the data and discuss with Novartis before the start of a phase II part. In the phase II part, investigators will compare the efficacy of the gemcitabine and cisplatin with or without RAD001 in patients with metastatic TNBC.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
National Cancer Center, Korea
Treatments:
Cisplatin
Everolimus
Gemcitabine
Sirolimus