Phase Ib, Dose Escalation Study of Oral LDE225 in Combination With BKM120 in Patients With Advanced Solid Tumors
Status:
Completed
Trial end date:
2015-04-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine the maximum dose of LDE225 and BKM120 that can be
safely given together to patients and/or the dose that will be used in future studies. This
study will also learn more about how the combination of these two investigational drugs may
work for patients with certain cancers (specifically metastatic breast cancer, advanced
pancreatic adenocarcinoma, metastatic colorectal cancer and recurrent glioblastoma
multiforme).