Overview

Phase III Trial of EBV-DNA-Guided Adaptive Immunotherapy for Advanced Nasopharyngeal Carcinoma

Status:
NOT_YET_RECRUITING
Trial end date:
2031-05-23
Target enrollment:
Participant gender:
Summary
This trial evaluated the efficacy of two adjuvant regimens following identical induction and concurrent chemoradiotherapy (IC+CCRT) in locoregionally advanced nasopharyngeal carcinoma (LANPC) patients with persistent EBV DNA positivity or stable disease after three IC cycles. The control arm received adjuvant adebrelimab, while the experimental arm received adebrelimab plus capecitabine.
Phase:
PHASE3
Details
Lead Sponsor:
Sun Yat-sen University
Treatments:
Capecitabine
Cisplatin
Immune Checkpoint Inhibitors
Radiotherapy, Intensity-Modulated