Phase III Randomized Study of Sodium Dichloroacetate in Children With Congenital Lactic Acidosis
Status:
Completed
Trial end date:
2002-09-01
Target enrollment:
Participant gender:
Summary
OBJECTIVES:
I. Compare the safety of sodium dichloroacetate (DCA) vs placebo in children with congenital
lactic acidosis.
II. Determine the quality of life of these patients.
III. Determine the pharmacokinetics and metabolic fate of DCA over the course of drug
administration in these patients.