Phase III Randomized Study of High Vs Standard Dose of Interferon Alfa for Chronic Hepatitis C
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
OBJECTIVES: I. Determine whether the initial response to interferon alfa (IFN-A) can be
increased by starting at a dose of 5 MU three times a week in patients with chronic hepatitis
C.
II. Determine whether patients who had normalized alanine aminotransferase (ALT) levels can
maintain normal ALT during stepwise dose reduction from 5 MU to 3 MU to 1.5 MU.