Overview

Phase III Double Blind Trial of Valproate Sodium for Prophylaxis of Post Traumatic Seizures

Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
OBJECTIVES: I. Determine whether treating head injured patients with valproate sodium will reduce the risk of developing seizures as a result of the head injury. II. Determine the safety of valproate, the appropriate dose, and the effect valproate may have on the recovery of the brain's ability to compute numbers, solve problems, remember information, and control the movement of limbs after head injury.
Phase:
Phase 3
Details
Lead Sponsor:
National Institute of Neurological Disorders and Stroke (NINDS)
Collaborator:
Harborview Injury Prevention and Research Center
Treatments:
Phenytoin
Valproic Acid