Overview

Phase II Trial of Pentostatin and Targeted Busulfan

Status:
Completed
Trial end date:
2013-08-01
Target enrollment:
Participant gender:
Summary
The objective of this trial is to determine whether a regimen of pentostatin and busulfan (IV) can facilitate engraftment of human leukocyte antigen (HLA) partially compatible siblings and unrelated donor transplants by using CD4+ laboratory-guided immunosuppression among 41 transplant patients meeting the inclusion criteria.
Phase:
Phase 2
Details
Lead Sponsor:
H. Lee Moffitt Cancer Center and Research Institute
Treatments:
Busulfan
Pentostatin
Rituximab