Overview

Phase II Trial of Bortezomib and Doxorubicin in Metastatic Breast Cancer

Status:
Terminated
Trial end date:
2009-10-01
Target enrollment:
Participant gender:
Summary
Primary objective is to determine the effectiveness of the combination of bortezomib and doxorubicin in patients with metastatic breast cancer. The trial format is a single arm Phase II design wherein patients are treated with bortezomib IV on days 1, 4, 8, and 11 and with doxorubicin IV on days 1 and 8 of a 21-day cycle.
Phase:
Phase 2
Details
Lead Sponsor:
University of Wisconsin, Madison
Collaborators:
Millennium Pharmaceuticals, Inc.
National Cancer Institute (NCI)
Treatments:
Bortezomib
Doxorubicin
Liposomal doxorubicin