Overview

Phase II Trial of Aprepitant & Palonosetron for CINV Prevention w FOLFOX

Status:
Completed
Trial end date:
2008-07-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Aprepitant, palonosetron, and dexamethasone may help lessen or prevent nausea and vomiting in patients receiving chemotherapy. PURPOSE: This phase II trial is studying how well giving aprepitant together with palonosetron and dexamethasone works in preventing nausea and vomiting caused by chemotherapy in patients receiving chemotherapy for metastatic colorectal cancer.
Phase:
Phase 2
Details
Lead Sponsor:
OHSU Knight Cancer Institute
Collaborator:
National Cancer Institute (NCI)
Treatments:
Aprepitant
BB 1101
Camptothecin
Dexamethasone
Dexamethasone 21-phosphate
Dexamethasone acetate
Fluorouracil
Fosaprepitant
Irinotecan
Leucovorin
Levoleucovorin
Oxaliplatin
Palonosetron