Phase II Study of Bone Marrow Transplantation Using Related Donors in Patients With Aplastic Anemia

• Status: Completed
• Trial end date: 1969-12-31

Summary

OBJECTIVES: I. Evaluate the efficacy of related, HLA-identical bone marrow transplantation following cyclophosphamide (CTX) and antithymocyte globulin in patients with aplastic anemia.

II. Evaluate the efficacy of related, HLA-nonidentical bone marrow transplantation following CTX and total-body irradiation/total-lymphoid irradiation in patients with aplastic anemia.

• Phase: Phase 2

Details

• Lead Sponsor: National Center for Research Resources (NCRR)
• Collaborator: University of California, Los Angeles
• Treatments: Antilymphocyte Serum; Cyclophosphamide; Cyclosporine; Cyclosporins; Methotrexate; Methylprednisolone; Methylprednisolone acetate; Methylprednisolone Hemisuccinate; Prednisolone; Prednisolone acetate; Prednisolone hemisuccinate; Prednisolone phosphate