Phase I Study of Mitoxantrone and Etoposide Combined With Hydroxychloroquine, for Relapsed Acute Myelogenous Leukemia
Status:
Terminated
Trial end date:
2017-10-02
Target enrollment:
Participant gender:
Summary
This is an open label phase I clinical trial of hydroxychloroquine (HCQ) ,when it is combined
with the usual medications for acute myeloid leukemia, mitoxantrone and etoposide. The
purpose of this study is to find the safest and most effective dose of hydroxychloroquine
with these medications. The investigators will be testing to see if it can increase the
effectiveness of mitoxantrone and etoposide.