Overview

Phase I Study of MLN8237 and Pazopanib in Patients With Solid Tumors

Status:
Completed
Trial end date:
2016-07-28
Target enrollment:
Participant gender:
Summary
This phase I trial using the EffTox design will evaluate activity and safety of alisertib, an Aurora A kinase inhibitor, when given in combination with the selective VEGFR inhibitor pazopanib in patients with advanced, previously treated non-hematologic solid tumors.
Phase:
Phase 1
Details
Lead Sponsor:
University of Illinois at Chicago
Collaborator:
Millennium Pharmaceuticals, Inc.