Phase I Study of IMRT and Molecular-Image Guided Adaptive Radiation Therapy for Advanced HNSCC
Status:
Terminated
Trial end date:
2016-09-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Specialized radiation therapy that delivers a high dose of radiation directly to
the tumor may kill more tumor cells and cause less damage to normal tissue. CT and PET scans
and treatment-planning systems may help in planning radiation therapy. Drugs used in
chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells,
either by killing the cells or by stopping them from dividing. Giving radiation therapy
together with cisplatin may kill more tumor cells.
PURPOSE: This phase I trial is studying the side effects and best dose of intensity-modulated
image guided adaptive radiation therapy when given together with cisplatin in treating
patients with locally advanced head and neck squamous cell cancer