Overview Phase I Study of GW572016 With Topotecan to Treat Advanced Solid Malignancies Status: Completed Trial end date: 2006-11-01 Target enrollment: Participant gender: Summary Participants will take GW572016 by mouth daily each cycle (cycles 28 days in length) and will be given Topotecan intravenously on Days 1, 8 and 15. Phase: Phase 1 Details Lead Sponsor: Mayo ClinicCollaborator: GlaxoSmithKlineTreatments: LapatinibTopotecan