Phase I Study of Capecitabine in Combination With Cisplatin and Irinotecan
Status:
Completed
Trial end date:
2009-01-01
Target enrollment:
Participant gender:
Summary
1. To determine the safety and feasibility of administering Capecitabine with the
combination of Cisplatin and Irinotecan.
2. To determine the Phase II recommended dose and toxicity profile of Capecitabine with the
combination of Cisplatin and Irinotecan.
3. To study the biologic effect of pyrimidine inhibition on DNA repair after camptothecin
therapy.