Phase I One-month Safety, PK, PD, and Acceptability Study of IVR Releasing TFV and LNG or TFV Alone
Status:
Completed
Trial end date:
2015-12-01
Target enrollment:
Participant gender:
Summary
The purpose of the study is to evaluate the safety of the TFV/LNG intravaginal ring (IVR),
TFV-only IVR, and placebo IVR, evaluate pharmacokinetics (PK) of TFV and LNG, evaluate
pharmacodynamic (PD) surrogates of contraceptive efficacy of LNG, and to evaluate
acceptability of the IVRs.