Overview

Phase I Newly Diagnosed GBM With Temozolomide, Radiation, and Minocycline Followed by Adjuvant Minocycline/Temozolomide (D-TERMINED)

Status:
Completed

Trial end date:
2018-02-18

Target enrollment:

Participant gender:

Summary

This will be an open label, single arm study. Subjects with newly diagnosed high grade glioma will begin minocycline one week prior to beginning postoperative chemoradiation and continue it until progression, intolerance, or the end of adjuvant temozolomide, whichever comes first.

Phase:

Phase 1

Details

Lead Sponsor:

University of Utah

Treatments:

Dacarbazine
Minocycline
Temozolomide