Overview

Phase I Methodology Study to Validate the Cantharidin Blister Model in Healthy Volunteers

Status:
Completed
Trial end date:
2011-01-14
Target enrollment:
Participant gender:
Summary
The purpose of this study is to refine the cantharidin-induced blister assay in healthy volunteers as a model of inflammatory disease. The study is an experimental trial in healthy volunteers in two parts; Part 1 to optimise the model and Part 2 to validate using two anti-inflammatory treatments with different modes of action.
Phase:
Phase 1
Details
Lead Sponsor:
GlaxoSmithKline
Treatments:
Aspirin
Cantharidin
Methylprednisolone
Methylprednisolone Acetate
Methylprednisolone Hemisuccinate
Prednisolone
Prednisolone acetate
Prednisolone hemisuccinate
Prednisolone phosphate