Phase I/II Study of Weekly Abraxane and RAD001 in Women With Locally Adv. or Metastatic Breast Ca
Status:
Terminated
Trial end date:
2015-08-12
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as paclitaxel albumin-stabilized nanoparticle
formulation, work in different ways to stop the growth of tumor cells, either by killing the
cells or by stopping them from dividing. Everolimus may stop the growth of tumor cells by
blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.
Giving paclitaxel albumin-stabilized nanoparticle formulation together with everolimus may
kill more tumor cells.
PURPOSE: This phase I/II trial is studying the side effects and best dose of everolimus when
given together with paclitaxel albumin-stabilized nanoparticle formulation and to see how
well it works in treating women with locally advanced or metastatic breast cancer.