Phase I / II Study of Irinotecan (CPT-11) Combined With l-Leucovorin (l-LV) and 5-FU in Patients With Advanced Colorectal Cancer

• Status: Completed
• Trial end date: 2004-11-01

Summary

We performed a phase I/II study of CPT-11/5FU/l-LV in advanced colorectal cancer, to determine the optimal dose of CPT-11 and to estimate the safety and efficacy of this regimen

• Phase: Phase 1/Phase 2

Details

• Lead Sponsor: Hokkaido Gastrointestinal Cancer Study Group
• Treatments: Camptothecin; Fluorouracil; Irinotecan; Leucovorin; Levoleucovorin