Overview

Phase I-II Everolimus and Sorafenib in Recurrent High-Grade Gliomas

Status:
Completed
Trial end date:
2021-07-13
Target enrollment:
Participant gender:
Summary
The goal of Phase 1 of this clinical research study is to find the highest tolerable dose and best schedule of the combination of everolimus and sorafenib that can be given to patients with malignant glioma. The goal of Phase 2 of this study to learn if the combination of everolimus and sorafenib can help to control malignant glioma. The safety of this combination will also be studied in both phases.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
National Cancer Institute (NCI)
Treatments:
Everolimus
Niacinamide
Sirolimus
Sorafenib