MP4OX is being developed as an ischemic rescue therapy to perfuse and oxygenate tissues at
risk during hemorrhagic shock. MP4OX is a pegylated hemoglobin-based colloid designed to
improve perfusion and target delivery of oxygen to ischemic tissues. This study will evaluate
safety and efficacy of MP4OX treatment, in addition to standard therapy, in trauma patients
suffering from lactic acidosis due to severe hemorrhagic shock.