Overview

Phase 2 Healthy Volunteer Study to Evaluate the Ability of PRT064445 to Reverse the Effects of Several Blood Thinner Drugs on Laboratory Tests (Module 4 of 4)

Status:
Completed
Trial end date:
2015-09-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to evaluate the ability of PRT064445 to reverse the effects of several blood thinner drugs on laboratory tests. The study also is evaluating the blood levels of PRT064445 given at different doses.
Phase:
Phase 2
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Portola Pharmaceuticals
Treatments:
Edoxaban
Criteria
Inclusion Criteria:

- Healthy men or women between the ages of 18 and 45 years old

Exclusion Criteria:

- History (including family history) or symptoms of, or risk factors for bleeding

- History (including family history) of or risk factors for a hypercoagulable or
thrombotic condition

- Absolute/relative contraindication to anticoagulation or treatment with specific
anticoagulants

- History of major surgery, severe trauma or bone fracture within 3 months prior to
dosing; or planned surgery within 1 month after dosing