Overview

Phase 2 Etirinotecan Pegol in Refractory Brain Metastases & Advanced Lung Cancer / Metastatic Breast Cancer

Status:
Completed
Trial end date:
2019-07-01
Target enrollment:
Participant gender:
Summary
This phase 2 trial evaluates how well pegylated irinotecan (NKTR-102) works in treating patients with non-small cell lung cancer (NSCLC), small cell lung cancer (SCLC), or breast cancer (mBC) that has spread to the brain and does not respond to treatment. Pegylated irinotecan may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Phase:
Phase 2
Details
Lead Sponsor:
Joel Neal
Stanford University
Collaborators:
National Cancer Institute (NCI)
Nektar Therapeutics
Treatments:
Camptothecin
Etirinotecan pegol
Irinotecan